Cytokine Receptor gp130

A cytokine receptor that contains extracellular FIBRONECTIN TYPE III DOMAINS which mediate its function through the formation of oligomeric complexes with itself, or with a variety of CYTOKINE RECEPTORS. It does not bind IL-6, but activates JANUS KINASES and STAT3 TRANSCRIPTION FACTOR.

Also Known As:

IL-6 Family Receptor gp130; IL-6 Receptor Signal Transducer gp130; IL6ST gp130; Interleukin-6 Receptor Subunit Beta; Signal Transducer gp130; Signal-Transducing Receptor gp130; Soluble Glycoprotein 130; Soluble gp130; gp130 IL-6 Family Receptor; gp130 Signal Transducer; gp130 Transducing Protein; sgp130; Glycoprotein 130, Soluble; Interleukin 6 Receptor Subunit Beta; Receptor gp130, Signal-Transducing; Signal Transducer, gp130; Signal Transducing Receptor gp130; gp130 IL 6 Family Receptor; gp130, Cytokine Receptor; gp130, Signal Transducer; gp130, Signal-Transducing Receptor; gp130, Soluble; Antigens, CD130; CD130 Antigens

Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Membrane Proteins: 10078
    - Cell Surface Receptors: 2125
      - Peptide Receptors: 1159
        Growth Factor Receptors: 2663
        Nerve Growth Factor Receptors: 526
        Ciliary Neurotrophic Factor Receptor: 32
        Cytokine Receptor gp130: 208
      - Immunologic Receptors: 9
        Cytokine Receptors: 1620
        Interleukin Receptors: 114
        Interleukin-6 Receptors: 1550
        Cytokine Receptor gp130: 208
        Interleukin-11 Receptors: 63
        Cytokine Receptor gp130: 208
        OSM-LIF Receptors: 84
        Cytokine Receptor gp130: 208
        Oncostatin M Receptors: 57
        Type II Oncostatin M Receptors
        Cytokine Receptor gp130: 208

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Disease

Drug/Important Bio-Agent (IBA)